The tests were carried out over albino mice taking different concentration of seed extract. Seeds extract of Dolichos biflorus has exhibited mild analgesic activity, the results
were (84.6 +/- 6.68) at dose 300mg/kg and (92.2 +/- 6.81) at dose 500mg/kg which were not much significant as compared to reference drug Aspirin (300mg/kg) having result (36.4 +/- 2.27). While seed extract of Dolichos biflorus exhibited remarkable diuretic activity, the values at 300 mg/kg was (1.33 +/- 0.13) and at 500 mg/kg were (2.66 +/- 0.31) which are highly significant as compared to drug Lasix (20mg /kg) having result (2.38 +/- 0.23). Anti-inflammatory effects of crude extract of Dolichos biflorus obtained at 0.06mg/kg and 01mg/kg were (26.6 +/- 2.96) and (36 +/- 1.67) respectively. While the value for aspirin as standard drug (300mg/kg) were (17.44 +/- 1.59).This study provides a platform Selumetinib concentration for further investigation for the isolation of active principles responsible for biological activity.”
“Wound healing is
actually a complex, precisely coordinated interaction between inflammatory cells and mediators, establishing significant overlap between the phases of wound healing. Chronic wounds are defined as wounds that do not follow the well-defined stepwise process of physiologic healing. The true incidence and economic impact of chronic wounds are difficult to assess because of the wide range of causative diseases and available see more treatment options. Despite multiple simultaneous and sequential therapeutic approaches, chronic wounds are highly resistant to treatment and are often indolent or even slowly progressive. Hyperbaric oxygen therapy (HBOT) has been explored as a treatment modality for chronic wounds because of its potential to promote healing and reduce bioburden in the wound bed. Multiple potential beneficial effects for wound healing have been demonstrated in various laboratory studies and experimental animal models. In this manuscript, HBOT, its mechanism of action, adverse effects
and usage in diabetic and nondiabetic chronic wounds have been reviewed.”
“Background and objective: The risk of pneumonia is increased among COPD patients using inhaled corticosteroids (ICS). However, there is uncertainty regarding the association between long-term use of ICS and exacerbations of respiratory ML323 mw tract infections among asthmatic patients.
Methods: A case-control nested cohort study was performed to assess the association of asthma with nontuberculous mycobacterium (NTM) infection.
Results: Among this cohort of 464 asthmatic patients, 14 experienced complications due to NTM infections, of which eight were caused by Mycobacterium avium-intracellulare complex, three by M. kansasii, one by M. terrae and the remaining two by unclassifiable scotochromogens. Asthmatic patients with NTM infections were older (67.1 +/- 8.6 vs 58.8 +/- 12.3 years, P < 0.