The histological evaluation did not reveal inflammatory cells and fibrosis in the piperacillintazobactam coated beta-TCP group. In contrast, the control group showed numerous inflammatory cells around the implanted uncoated beta-TCP granules and incomplete new bone formation.
Conclusion: beta-TCP is an effective carrier material for piperacillin-tazobactam. The use of piperacillintazobactam coated beta-TCP may be optimal for mastoid obliteration. (C) 2011 Elsevier Ireland Ltd. All rights reserved.”
“Purpose: To review the results of metallic urethral stents
used in patients with neuropathic buy Autophagy Compound Library bladder dysfunction after spinal cord injury (SCI).
Patients and Methods: In a rehabilitation unit for SCI and stroke in Cape Town, South Africa, we performed a case note review of dual flange Memokath stents placed from March 2008 until October 2011. Stents were placed rather than performing an external sphincterotomy in selected patients. With the patient under deep general anesthesia, a thermosensitive expandable metallic stent was positioned over the internal and external urethral sphincters.
Results: In total, 33 stents were placed in 28 male patients. SCI was cervical in 23 patients and thoracic in 5. Average follow-up was 18 months
(range 1-40 months, median 18 months). The most common indications were repeated catheter blockage Selleck A-1210477 in eight patients and urinary tract infection in six. The average time from SCI to stent insertion was 79 months (range 1-468 months, median 21 months). Trichostatin A mw Severe autonomic dysreflexia was present in
17 cases before stent placement and in 7 after stents were placed (P = 0.003). Stents failed in 15 patients (45%) and were removed. The most common reason for failure was stone formation. Comparing the group of patients with stents lasting >20 months (n = 11) to the group with stent removal before 20 months (n = 10), the mean time between SCI and stent placement was 31 vs 119 months (P = 0.057). Medium term results (up to 27 months) were significantly influenced by earlier stent placement (P = 0.0484). One major complication was stent migration that caused an urethrocutaneous fistula.”
“Objectives: Finding a resolution of middle ear effusion using myringotomy, or dry tap (DT), is relatively common, but its clinical outcome is confounded by general anesthesia (GA). The confounding effect of GA and a time delay can be removed because laser myringotomy can be completed under topical anesthesia, which is a routine procedure for otitis media with effusion (OME) before GA in our clinic. DT without GA would clarify the clinical outcome, and the percentage of recurrence for OME after DT would be clinically relevant.