(Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107:625-629)”
“Objectives: This study’s aim was to evaluate changes of serum aldosterone concentration after successful cardioversion of persistent AF and to determine the prognostic value of these changes.
Methods: The prospective, single center study included 45 consecutive patients with nonvalvular persistent AF and preserved left ventricular systolic function, selleck chemicals llc referred for cardioversion. None of the patients were taking aldosterone antagonists. Blood samples for aldosterone measurement
were collected twice: 24 hours before and 24 hours after cardioversion.
Results: Forty-three patients were successfully converted to sinus rhythm. On the 30th day following cardioversion, 24 patients
maintained sinus rhythm (group A), 19 patients relapsed to AF (group B). Serum aldosterone concentration before cardioversion did not differ significantly between both groups (175.6 +/- 112.82 pg/mL vs 125.8 +/- 51.2 pg/mL; P = 0.25). However, in group A serum aldosterone level decreased significantly within 24 hours after cardioversion, from 175.6 +/- 112.8 pg/mL to 101.4 +/- 44.2 pg/mL (P = 0.0034). In group B, the aldosterone level before and after cardioversion did not differ significantly (125.8 +/- 51.2 pg/mL vs 118.2 +/- 59.6 pg/mL; P = 0.68). Logistic regression analysis revealed that a decrease in plasma aldosterone concentration after direct current cardioversion more than 13.2 pg/mL MAPK inhibitor predicted sinus rhythm maintenance in a 30-day follow-up, with 87% sensitivity and 64% specificity.
Conclusions: There is a positive correlation between the fall in aldosterone concentration 24 hours after cardioversion and maintenance of sinus rhythm during
30 days of observation. (PACE 2010; 561-565).”
“Migraine is a common neurological disorder of unclear pathogenesis. Recently incompetence of internal jugular vein valve (IJVVI) was found to be associated with some neurological conditions of unknown etiology such as benign cough headache, primary exertional headache or transient global amnesia. Common vascular mechanism linking transiently increased cerebral venous pressure with the above mentioned conditions was then postulated. Therefore we decided to investigate whether IJVVI may be associated with migraine.
The aim of our study was to evaluate the occurrence of IJVVI and retrograde MK-8776 flow duration in 70 (56 females) migraine patients by color Doppler ultrasound during Valsalva maneuver.
We assessed internal jugular vein valve in 44 patients with migraine without aura (39 female); mean age 37 +/- 9 yrs. and in 26 patients with migraine with typical aura (17 female); mean age 34 +/- 9 yrs. Age- and sex-matched control group consisted of 42 healthy persons (33 female); mean age 32 +/- 1 yrs.
Frequency of the internal jugular vein valve insufficiency was similar in patients with migraine and in the healthy subjects (51% v. 40%, p = 0.26).