Objective: We examined whether dietary intakes of vitamins B-6, folate, or vitamin B-12 were predictive of depressive symptoms over an average selleck kinase inhibitor of 7.2 y in a community-based population of older adults.

Design: The study sample consisted of 3503 adults from the Chicago Health and Aging project, an ongoing, population-based, biracial (59% African American) study in adults aged >= 65 y. Dietary assessment was made by food-frequency questionnaire. Incident depression was measured by the presence

of >= 4 depressive symptoms from the 10-item version of the Center for Epidemiologic Studies Depression scale.

Results: The logistic regression models, which used generalized estimating equations, showed that higher total intakes, which included supplementation, of vitamins B-6 and B-12 were associated with a decreased likelihood of incident depression for up to 12 y of follow-up, after adjustment for age, sex, race, education, income, and antidepressant medication

use. For example, each 10 additional milligrams of vitamin B-6 and 10 additional micrograms of vitamin B-12 were associated with 2% lower odds of depressive symptoms per year. There was no association between depressive symptoms and food intakes of these vitamins or folate. These associations remained after adjustment for smoking, alcohol use, widowhood, caregiving status, cognitive function, physical disability, and medical conditions.

Conclusion: Our results support selleck the hypotheses that high total intakes of vitamins B-6 and B-12 are protective of depressive symptoms over time in community-residing

older adults. Am J Clin Nutr 2010; 92: 330-5.”
“We investigate the influence of lattice distortion and off-stoichiometry on the electronic and magnetic properties of Co2+xFe1-xSi Heusler alloys in their L2(1) bulk phase and on MgO(001) buy ATM Kinase Inhibitor using the density functional theory. Our investigations show that Co excess does not significantly change the magnetic properties, whereas an increase of the Fe content can reduce the spin polarization. In addition, the influence of off-stoichiometry on x-ray absorption spectra is studied. For comparison, x-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) measurements have been carried out for Co2FeSi/MgO(001) at the Co and Fe L-2,L-3 edges. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3559487]“
“A novel polyurethane material containing zwitterionic sulfobetaine groups has been synthesized using the copper-catalyzed 1,3-dipolar cycloaddition (azide-alkyne click chemistry). A standard two-step polyaddition method was used to produce the well-defined polyurethane based on polycarbonatediol (PCDL) with alkyne groups.