(C) 2011 American Institute

of Physics [doi 10 1063/1 35

(C) 2011 American Institute

of Physics. [doi.10.1063/1.3599895]“
“Purpose: To assess tumor perfusion with multi-detector row computed tomography (CT) in patients with non-small cell lung carcinoma and to correlate CT findings with pathologic results.

Materials and Methods: This study was approved by the local Ethics Committee, and all patients provided written informed consent, which included information on the radiation exposure at the CT examinations. Fifteen consecutive patients (mean age, 60.5 years +/- 7.7 [standard eFT508 molecular weight deviation]), including 14 men (mean age, 59.9 years +/- 7.5) and one woman (age, 70 years) with histologically proved non-small cell lung carcinoma were prospectively enrolled. Overall, pathologic-CT correlations were examined in 31 focal tumoral zones. Comparative analysis was performed by using the chi(2) or the Fisher exact test for categoric data. For numeric data, group comparisons were performed by using the Mann-Whitney test.

Results: Whole-tumor coverage (mean height, 4.3 cm +/- 2.1) was possible in all patients with generation of colored parametric maps of volume transfer constant (K-trans) and blood volume (BV) by using Patlak analysis. Of the 12 areas that showed high BV, 10 (83%) had a high K-trans; in all 12 cases, the vascular score was high, confirming the presence of numerous tumoral vessels. Nineteen areas showed low BV; when observed

concurrently with a high K-trans (seven of 19), the AZD4547 purchase mean vessel number per area was significantly Epacadostat mouse higher than that seen in areas with low BV and low K-trans (12 of 19) (P = .038), suggestive of tumoral vessels associated with high interstitial pressure.

Conclusion: Whole-tumor perfusion analysis is technically feasible with 64-detector row CT, with two patterns suggestive of high tumoral vascularity. (C) RSNA, 2010″
“A computational study

of the effects of the intergranular exchange field and its dispersion on the cluster size in perpendicular recording media is presented. The dispersion arises from the grain size dispersion and the dispersion of intrinsic exchange coupling between individual grains. It is found that increasing the degree of dispersion reduces the cluster size due to weakly coupled grains acting as pinning sites against the expansion of the clusters. A simple semi-analytical model is proposed which gives good agreement with the numerical calculations in the limit of the large anisotropy constant. (c) 2011 American Institute of Physics. [doi:10.1063/1.3596806]“
“We made a study of the prevalence of human papillomavirus (HPV) and cervix lesions in an Amazonian Bora native population (Bn) and compared it with the prevalence in an urban population in Iquitos (Iq). We also examined the distribution of HPV types among abnormal cervical smears in the Iq population. Swabs and cytologies were collected from 472 females.

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