All compound groups showed a weak decreasing trend over the study period, which was statistically significant for HCB and close to being significant for Sigma HCH. The weak decrease of Sigma PCB and Sigma DDT is different from other time trend studies from Greenland, usually showing a more pronounced decrease in the beginning of the study period, followed by a certain stabilisation in recent years. (C) 2008 Elsevier Ltd. All rights reserved.”
“Purpose of review
Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity
and mortality in low birth weight infants. Although decades of research point to a role for gut bacteria in the pathogenesis of the disease, the exact relationship between microbes and NEC has not been elucidated. In this review, we describe recent advances in the use of molecular methods to compare gut bacteria in infants with and without NEC.
Recent findings
Our understanding of how bacteria contribute to NEC pathogenesis https://www.selleckchem.com/products/gs-9973.html find more has been limited by the use of traditional, culture-based investigations. Recent advances in microbial ecology and DNA sequencing have made it possible to comprehensively study gut bacterial
populations and to understand their physiologic importance. Several studies have identified differences in the microbiota among infants with and without NEC, but the findings have often varied across studies.
Summary
To date, no single change in the gut microbiota has definitively been identified as a risk factor or cause of NEC. The findings at present suggest that 3-deazaneplanocin A Epigenetics inhibitor NEC does not result from growth of a single causative pathogen, but rather that the disease results from a generalized disturbance of normal colonization patterns in the developing
gut.”
“Prostratin, a tigliane phorbol ester with promise for the treatment of HIV, was identified and quantified in Euphorbia fischeriana root extracts obtained from several different sites in China. The greatest yield was recovered from root samples collected from Yakeshi, Inner Mongolia (63.54 mu g/g dry weight, or 0.00635% by mass). Prostratin was not detected in extracts of Euphorbia sp., E. esula, E. lucorum or Stellera chamaejasme. The presence of prostratin was verified by H-1 and C-13 NMR. Major fragmentation products were identified from ESI MSn spectra after HPLC separation, providing a reproducible fingerprint for unambiguously recognizing the compound in plant extracts. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.”
“Background and Purpose: Renal hematoma after ureteroscopic lithotripsy (URSL) using holmium:yttrium-aluminum-garnet (Ho:YAG) laser is a rare complication. We aimed to review our center’s experience of post-URSL subcapsular hematoma. Patients and Methods: From 2007 to 2012, 1114 URSLs using 7.5F semi-rigid ureteroscopes were performed. Patients with post-URSL symptomatic renal hematoma were reviewed.