Results: In 4 cases of abdominal mass, there was 1 castleman disease,1 maligant mesenchymal tumorin,1 schwannoma and 1 epithelioid mesotheliomas. The ultrasonoscopy and result of pathology and BI6727 cytology were showed in figure A(a), B(b), C(c) and D(d) Conclusion: Ultrasonographically guided puncture could make a definitive diagnose for abdominal mass and provides important value for clinical treatment. Key Word(s): 1. ultrasound-guided; 2. abdominal mass;

3. biopsy; Presenting Author: QIAN ZHANG Additional Authors: CHUNYU ZHANG, YONGGUI ZHANG, WENQIAN QI Corresponding Author: QIAN ZHANG Affiliations: China-Japan Union hospital of JiLin University Objective: PME/PDE ratio of 31p MRS was correlated better with the fibrosis score. This study was to investigate the utility of

31P MR spectroscopy as a noninvasive http://www.selleckchem.com/products/gdc-0068.html test to access the liver histology after pegylated interferon α-2a in chronic HBV patients. Methods: Patients initially received conventional Peg-IFNα-2a 180 μg (sc) once weekly for 48 weeks. Every patients was examined with 31p MRS (3.0T PHILIPS) when before antiviral therapy,24 weeks and 48weeks. Patients were divided into SVR group and no SVR group (sustained virologic response, SVR). Compare the 31p MRS PME/PDE of the same group patients at different therapy weeks, and the one of different group patients at the same therapy weeks. Results: Whenever the SVR group and no SVR group, PME/PDE ratio of 31p MRS at 48 weeks was significant lower than the one at24weeks, and the two were lower than the one before antiviral therapy. When 24weeks and 48weeks, PME/PDE ratio of 31p MRS in SVR group was significant lower than no SVR group, but this was not been seen when before antiviral therapy. Conclusion: The 31p MRS PME/PDE ratio decreased in chronic HBV patients during pegylated interferon α-2a antiviral therapy. 31p MRS PME/PDE ratio can be used as biomarkers in a noninvasive test of liver histology response to treatment. Key Word(s): 1. 31p MRS; 2. liver histology; 3. peg-IFN α-2a; 4. chronic HBV; Presenting Author: QIAN ZHANG Additional Authors: WENQIAN QI, CHUANYU ZHANG,

YONGGUI MCE ZHANG Corresponding Author: QIAN ZHANG, YONGGUI ZHANG Affiliations: China-Japan Union hospital of JiLin University Objective: PME/PDE ratio of 31p MRS was correlated better with the fibrosis score. This study was to investigate the correlations between 31P MRS and histological grading and staging in chronic HBV patients. Methods: 20 chronic HBV patients and 10 healthy volunteers was includes this study. 20 chronic HBV patients was examined with liver biopsy and 31p MRS, 10 healthy volunteers was examined with 31p MRS. In 31P MRS, peak area of PME, PDE, PCr, Pi, γ-ATP, β-ATP, α-ATP were calculated. Biospy specimens were socred for fibrosis and necroinflammation according to the Knodell histology index (HAI). Results: There were differences in PME%, PDE% and PME/PDE between chronic HBV and control group.